Investigate into of effective constituent transference of herba Ephedrae and cortex Magnoliae officinalis in preparation course of Shujin Kechuan capsule.
- Author:
Shuang-feng LIN
1
;
Xue-hong KE
;
Gang WEI
Author Information
- Publication Type:Journal Article
- MeSH: Asthma; drug therapy; Biphenyl Compounds; analysis; Capsules; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; chemistry; isolation & purification; therapeutic use; Ephedra sinica; chemistry; Ephedrine; analysis; Lignans; analysis; Magnolia; chemistry; Plant Structures; chemistry; Plants, Medicinal; chemistry; Technology, Pharmaceutical; methods
- From: China Journal of Chinese Materia Medica 2006;31(23):1950-1952
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEInvestigate into transport rate and retention rate transference of principal effective constituent in Shujin Kechuang capsule, a new development Chinese patent medicine for theraphy asthma.
METHODHPLC was applied to analyze the content of ephedrine hydrochloride and honokiol and magnolol in crude drugs and 60% ethanol extracting solution and 25% concentrated solution,50% concentrated solution, 100% concentrated solution and finished product ( Shujin Kechuang capsule).
RESULTThe transport rate of ephedrine hydrochloride and honokiol and magnolol is 56. 32%, 14. 43%, 14. 56% in the finished product respectively.
CONCLUSIONshould be concentrate and desiccation in the condition that decompress and low temperature.