Terpenoid compounds isolated from Ligularia sagitta.
- Author:
Shou-jin LIU
1
;
Mian ZHANG
;
Zheng-tao WANG
;
Jian-qun LIU
;
Chao-feng ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: 4-Butyrolactone; analogs & derivatives; chemistry; isolation & purification; Asteraceae; chemistry; Oleanolic Acid; analogs & derivatives; chemistry; isolation & purification; Plant Roots; chemistry; Plants, Medicinal; chemistry; Rhizome; chemistry; Sesquiterpenes; chemistry; isolation & purification; Terpenes; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2006;31(23):1965-1967
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of radix and rhizome of Ligularia sagitta.
METHODIsolation and purification were carried out on the column chromatography of silica gel and sephadex LH -20. The structures were identified by spectral analysis.
RESULTSeven terpenoid compounds were isolated from the radix and rhizome of L. sagitta. Five of them are sesquiterpenoids, the structures were determined as 7alpha-hydroxy-9(10) -ene-1, 8-dioxo-6, 7-dihydrofuranoeremophilane (1), 1p, 10P3-epoxy-6beta, 8 beta-dihydroxy-eremophil7 (11) -en-12, 8alpha-olide (2) , 1-oxo-9-desoxycacalol (3), benzofuranoeremophil-l-ene (4) and bakkenolide (5); other two compounds belong to triterpenoid. 3p, 16P3-dihydroxy-12-oleanen-28-al (6) and lupeol (7).
CONCLUSIONCompoundsl-3 and 6 were: isolated from L. sagitta for the first time, and compounds 3 and 6 were obtained from Ligularia for the first time.
