Cure effects of Jiangu Fufang on osteoporotic model induced by ovariectomy.
- Author:
Ying-Xian DENG
1
;
Zeng-Chun MA
;
Hong-Ling TAN
;
Cheng-Rong XIAO
;
Yu-Guang WANG
;
Yue GAO
Author Information
- Publication Type:Journal Article
- MeSH: Alkaline Phosphatase; blood; Animals; Biomechanical Phenomena; Bone Density; drug effects; Calcium; blood; Drug Combinations; Drugs, Chinese Herbal; isolation & purification; pharmacology; therapeutic use; Female; Femur; physiopathology; Lumbar Vertebrae; drug effects; pathology; physiopathology; Osteoporosis; blood; drug therapy; physiopathology; Ovariectomy; Phosphorus; blood; Phytotherapy; Plants, Medicinal; chemistry; Random Allocation; Rats; Rats, Sprague-Dawley
- From: China Journal of Chinese Materia Medica 2006;31(24):2070-2073
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the cure effects of Jiangu Fufang on osteoporotic model induced by ovariectomy.
METHODRats were ovariectomized and administered drugs for 3 monthes. Bone mineral density and biomechanics properties, histomorphometric analysis and biochemical index such as calcium, phosphorus, alkaline phosphatase were detected.
RESULTJiangu Fufang could significantly increase bone density and biomechanics properties. The level of calcium, phosphorus and alkaline phosphatase were restored by Jiangu Fufang. Jiangu Fufang could significantly increase area of bone trabecula, thickness of cortical bone and bone trabecula.
CONCLUSIONJiangu Fufang could cure osteoporosis through increasing bone mineral density, improving bone biomechanics properties, and effecting bone metabolism.
