Investigation on dissolution of cinnabar in vitro.
- Author:
Ke-wu ZENG
1
;
Qi WANG
;
Xiao-da YANG
;
Kui WANG
Author Information
- Publication Type:Journal Article
- MeSH: Cysteine; chemistry; Hydrogen-Ion Concentration; Mercury Compounds; analysis; chemistry; Particle Size; Solubility; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Sulfites; chemistry
- From: China Journal of Chinese Materia Medica 2007;32(3):231-234
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study effects of different chemical factors in gastrointestinal tract, i.e. pH, protein, amino acid, ionic strength, Na2S, on the dissolution of cinnabar.
METHODThe content of total mercury in various dissolution of cinnabar were analyzed by UV/VIS Spectrophotometer. The particle distributions in dissolution of cinnabar were measured by Laser Particle Size Analyzer. The constituents of dissoluble substance of cinnabar in presence of Na2S were determined using ESI-MS.
RESULTThe solubility of cinnabar could be increased significantly in the presence of Na2S/So, and strong acidic pH, respectively. While the influence of thiol amino acid on promoting dissolution remains relatively low. Cinnabar didnt dissolve mainly in the form of nanoparticle.
CONCLUSIONWe postulated that cinnabar could be dissolved in various forms of mercury complexes containing sulphur.
