A pilot study on the diagnosis of laryngopharyngeal reflux diseses
10.3760/cma.j.issn.1673-0860.2009.02.007
- VernacularTitle:咽喉反流的初步诊断
- Author:
Li-Hong ZHANG
1
;
Na LI
;
Hong-Wei ZHENG
;
Li-Sheng YU
;
Gui-Jian FEN
Author Information
1. 北京大学人民医院
- Keywords:
Laryngeal diseases;
Pharyngeal diseases;
Gastroesophageai reflux;
Hydrogen-ion concentration
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2009;44(2):105-108
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of the reflux symptom index (RSI) and reflux finding score (RFS) in laryngopharyngeal reflux disease(LPRD). Methods Twenty-five patients with RSI scores > 13 or RFS scores > 7 and sixteen patients with RSI scores > 13 and RFS scores > 7 were suspected as LPRD. Forty one patients with the RSI scores > 13 and/or RFS scores > 7 were suspected as LPRD, 15 patients with the RSI scores ≤ 13 and RFS scores ≤ 7 were regarded as control group. All the patients had 24-hour dual probe pH monitoring. Twenty-five patients with positive pH monitoring hand received anti-reflux treatment with omeprazole for 3 months, and then the RSI and RFS was estimated gain. Results The RSI and RFS scoring had high consistent with the results of pH monitoring (Kappa=0.43, u=3.48, P < 0.01),especially if RSI scores > 13 and RFS scores >7 (Kappa=0.55, u=3.06, P<0.01). There was a significant decreasing in RSI and RFS scoring in patients after anti-acid treatment for 3 months (tRSl=8.838, PRSl=0.000;tRFS=5.695, PRFS=0.000). Conclusions The RSI and RFS can be used as screening tool for laryngopharyngeal reflux diseases and as a simple method for evaluating the effectiveness of treatment.
