Treatment of allergic rhinitis with nasal mometasone furoate
10.3760/cma.j.issn.1673-0860.2009.06.004
- VernacularTitle:鼻用糠酸莫米松治疗中-重度变应性鼻炎的多中心临床研究
- Author:
Luo ZHANG
1
;
Geng XU
;
Xiang-Dong WANG
;
Shi-Xi LIU
;
Yuan LI
;
Shen-Qing WANG
;
Bei-Bei YANG
;
Chun-Quan ZHENG
;
Cheng-Shuo WANG
;
Pin DONG
;
Zi-Ping LIN
;
Hua ZHANG
;
De-Min HAN
Author Information
1. 首都医科大学附属北京同仁医院
- Keywords:
Rhinitis,allergic,Perennial;
Pregnadienediols;
Quality of life;
Multicenter study
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2009;44(6):455-459
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of nasal mometasone furoate on moderate to severe allergic rhinitis. Methods Patients with moderate to severe allergic rhinitis were enrolled and received mometasone furoate nasal spray 200 μg once daily for four weeks. Four hundreds and sixty-three patients completed the study. We weekly interviewed the patients to evaluate the symptoms, and the affection of disease on night sleep and daily life. Mini Rhinoconjunctivitis Quality of Life Questionnaire (Mini-RQLQ) and Nocturnal Rhinoconjunctivitis Quality of Life Questionnaire (NRQLQ) were used to evaluate the quality of life. Results The individual and total symptomatic scores of week 1, week 2 and week 4 decreased compared with baseline. The scores of Mini-RQLQ and NRQLQ of week 1, week 2 and week 4 decreased compared with baseline too. The scores of the next visit were significantly lower than those of the previous visit (P < 0. 01 ) . Conclusions A four-week administration of mometasone furoate nasal spray can effectively treat allergic rhinitis.
