Clinical Characteristics and Treatments of Patients with TSH Secreting Pituitary Adenoma.
- Author:
Dongsun KIM
1
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
- Publication Type:Editorial
- Keywords:
TSH producing pituitary adenoma;
Pituitary tumor, Somatostatin;
TSH
- MeSH:
Adenoma;
Humans;
Hyperthyroidism;
Pituitary Neoplasms;
Rare Diseases;
Somatostatin;
Thyroid Hormones
- From:Korean Journal of Medicine
2011;80(1):43-46
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
TSH secreting pituitary adenoma is a very rare disease, but it should be carefully suspected in patients with the lack of inhibition of TSH levels in the presence of increased thyroid hormones. The clinical manifestations are similar to those of hyperthyroidism, so TSH secreting pituitary adenoma can be easily misdiagnosed as hyperthyroidism resulting in inappropriate treatment. Surgery is the treatment of choice and the long-acting somatostatin analogs are effective in reducing TSH secretion with consequent restoration of the euthyroid state in the majority. Recently, development of neuroradiological techniques and better recognition of TSH-secreting adenomas increase the rate of diagnosis as microadenoma and improve surgical cure rate in patients with TSH secreting pituitary adenoma.
