A Case of Undifferentiated Carcinoma with Osteoclast-Like Giant Cells in the Pancreas.
- Author:
Suh Yoon YANG
1
;
Jae Hyuk DO
;
In Soo OH
;
Hyun Woong LEE
;
Chang Hwan CHOI
;
Sae Kyung CHANG
;
Eon Sub PARK
Author Information
1. Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea. jhdo@cau.ac.kr
- Publication Type:Case Report
- Keywords:
Pancreas;
Osteoclast-like giant cells;
Undifferentiated carcinoma
- MeSH:
Adenocarcinoma;
Aged;
Carcinoma;
Cellular Structures;
Dyspepsia;
Giant Cell Tumors;
Giant Cells;
Humans;
Hydrazines;
Magnetic Resonance Imaging;
Male;
Osteoclasts;
Pancreas;
Pancreatectomy;
Splenectomy
- From:Korean Journal of Medicine
2011;80(1):82-86
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Undifferentiated carcinomas with osteoclast-like giant cells are rare pancreatic and periampullary neoplasms that mimic giant cell tumors of bone morphologically. Recently, we experienced an osteoclast-like giant cell tumor arising in the tail of the pancreas. A 76-year-old male was admitted with epigastric discomfort and indigestion. Abdominal computed tomography (CT) and abdominal magnetic resonance imaging (MRI) showed a 3x3-cm mass containing necrotic and hemorrhagic areas in the tail of the pancreas. A distal pancreatectomy and splenectomy were performed. Histological examination showed tumor cell components consisting of mononuclear pleomorphic cells admixed with osteoclastic giant cells. The final diagnosis was undifferentiated carcinoma with osteoclast-like giant cells with ductal adenocarcinoma in the pancreas.
