Effect of Penqiangyan Granule on the immune function of patients with chronic pelvic inflammatory disease of blood-stasis and Shen-deficiency syndrome type.
- Author:
Rui-Fen LIU
;
Xiao-Na YANG
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; CD4-CD8 Ratio; Chronic Disease; Diagnosis, Differential; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Interleukin-2; blood; Male; Medicine, Chinese Traditional; Middle Aged; Pelvic Inflammatory Disease; diagnosis; drug therapy; immunology; Phytotherapy; Syndrome; Treatment Outcome; Tumor Necrosis Factor-alpha; blood; Yang Deficiency; diagnosis; drug therapy; immunology; Young Adult
- From: Chinese Journal of Integrated Traditional and Western Medicine 2007;27(9):841-843
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the effect of Penqiangyan Granule (PG) on the immunity of patients with chronic pelvic inflammatory disease (CPID) of blood stasis and Shen-deficiency syndrome (BSSDS) type.
METHODSSixty patients were randomly assigned to two groups: the treatment group treated with PG and the control group with Penyanjing Granule, 30 cases in each group. The treatment course was 4 weeks for both groups. The clinical efficacy, plasma levels of CD4 and CD8, and the serum levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-2 (IL-2) were measured before and after treatment.
RESULTSAfter treatment, the total effective rate in the treatment group and the control group was 96.7% and 63.3% respectively with significant difference between groups (P < 0.05); in the treatment group the plasma CD4, CD4/CD8 and serum IL-2 increased obviously, while the plasma CD8 and serum TNF-alpha decreased markedly (P < 0.05), all were significantly different with those in the control group (P < 0.05).
CONCLUSIONPG can improve the immune function and alleviate inflammation in CPID patients of BSSDS type.