Prevention and treatment of biliary complications following orthotopic liver transplantation.
- Author:
Yong-feng LIU
1
;
Gui-chen LI
;
Gang WU
;
Jia-lin ZHANG
;
Shu-rong LIU
;
Yi-man MENG
;
Ying CHENG
;
Lei YANG
;
Ming-jun SUN
;
Xi-tong ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Biliary Tract Diseases; etiology; prevention & control; therapy; Female; Humans; Liver Transplantation; methods; Male; Middle Aged; Postoperative Complications; prevention & control; therapy; Retrospective Studies
- From: Chinese Journal of Surgery 2008;46(12):911-913
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the prevention and treatment of biliary complications after orthotopic liver transplantation.
METHODSClinical data of 183 recipients who had received liver transplantation between May 1995 and December 2006 were retrospectively analyzed.
RESULTSBiliary complications occurred in 15 patients (15/183, 8.2%). The incidence for short-term and long-term complication were 6.0% (11/183) and 2.2% (4/183) respectively. No biliary complications was due to hepatic artery thrombosis(HAT). Four cases who received PTC(percutaneous transhepatic cholangiography) with stent insertion,8 cases who received ERCP( endoscopic retrograde cholangiopancreatography) with stent insertion and 1 who received Roux-en-Y choledochojejunostomy for anastomotic stricture were successfully cured. Two cases required relaparotomy died for fungus infection eventually. The mortality due to biliary complications was 1.1%.
CONCLUSIONSThe rapid combined abdominal organ harvesting technique could shorten the ischemia time and ameliorate the injury due to vascular and bile duct variances, which could reduce the incidence of biliary complication. PTC and (or) ERCP combined with stent insertion were main procedure for biliary complications not related to HAT after liver transplantation.