Genetic polymorphism of 6 short tandem repeat loci in Chinese Korean.
- Author:
Xiaobo BU
1
,
2
;
Ying WANG
;
Jie SONG
;
Xiuzhi LI
;
Haihua BAO
;
Shujie ZHANG
;
Xueling GAO
Author Information
- Publication Type:Journal Article
- MeSH: Alleles; China; DNA; genetics; Gene Frequency; Genotype; Humans; Korea; ethnology; Polymorphism, Genetic; genetics; Tandem Repeat Sequences; genetics
- From: Chinese Journal of Medical Genetics 2002;19(3):230-233
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze genetic polymorphism of D16S539 D7S820 D13S317 CSF1PO TPOX and TH01 in Chinese Korean.
METHODSOne hundred unrelated individuals were analyzed by PCR amplification fragment length polymorphism analysis.
RESULTSSix alleles and 18 genotypes of D16S539 locus, 7 alleles and 22 genotypes of D7S820 locus, 7 alleles and 23 genotypes of D13S317 locus, 6 alleles and 16 genotypes of CSF1PO locus, 6 alleles and 11 genotypes of TPOX locus, 5 alleles and 12 genotypes of TH01 locus.
CONCLUSIONThe genotype distribution of all the 6 short tandem repeat(STR) in Chinese Korean met Hardy-Weinberg equilibrium, and have higher heterozygosities. The data obtained can be used in human identity and paternity testing, and in other genetic researches and population investigation.
