Acupuncture inhibiting responses of spinal dorsal dorsal horn neurons induced by noxious dilation rectum and colon.
- Author:
Pei-jing RONG
1
;
Bing ZHU
;
Qi-fu HUANG
;
Xin-yan GAO
;
Hui BEN
;
Yan-hua LI
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Colon; innervation; Nociceptors; Posterior Horn Cells; Rats, Sprague-Dawley; Rectum; Spinal Cord
- From: Chinese Acupuncture & Moxibustion 2005;25(9):645-650
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study on mechanisms of acupuncture in relieving visceral pain.
METHODSIn SD rats CRD was used as noxious visceral stimuli. Activities of spinal dorsal horn wide dynamic (WDR) neurons of L1-L13 were recorded by extracellular microelectrode technique. Acupuncture was given at ipsi-lateral and contra-lateral Zusanli (ST 36) of the same segmental innervation of rectum and colon.
RESULTSVisceral noxious afferent could significantly activate spinal dorsal horn convergent neurons, and mechanical stimulation of contra-lateral body surface and hand acupuncture at Zusanli (ST 36) could inhibit this noxious response. When the spinal cord was acutely blocked, the inhibiting CRD effect of needling CRD effect of needling contra-lateral Zusanli (ST 36) completely disappeared.
CONCLUSIONAcupuncture and visceral noxious afferent signals converge and interact each other in spinal level, and acupuncture at acupoint can inhibit the spinal dorsal horn neuron respon se activated by visceral noxious afferent and this action needs the participation of the center above the spinal cord.
