Studies on chemical constituents from fruits of Morus alba L.
- Author:
Xin WANG
;
Hong-Qing WANG
;
Jie KANG
;
Chao LIU
;
Ruo-Yun CHEN
- Publication Type:Journal Article
- MeSH:
Chlorogenic Acid;
isolation & purification;
Esters;
Fruit;
chemistry;
Furans;
chemistry;
isolation & purification;
Lactams;
isolation & purification;
Molecular Structure;
Morus;
chemistry;
Plants, Medicinal;
chemistry;
Pyrrolidonecarboxylic Acid;
isolation & purification;
Tricarboxylic Acids;
chemistry;
isolation & purification
- From:
Acta Pharmaceutica Sinica
2014;49(4):504-506
- CountryChina
- Language:Chinese
-
Abstract:
Chemical investigation of fruits of Mours alba L. lead to the isolation of fifteen compounds by various chromatographies such as silica gel, Sephadex LH-20, RP-C18 column chromatography. Their structures were determined to be: 1-[5-(2-formlfuryl) methyl] dihydrogen 2-hydroxypropane-1, 2, 3-tricarboxylate 2, 3-diethyl ester (1), 1-[2-(furan-2-yl)-2-oxoethyl] pyrrolidin-2-one (2), divaricataester A (3), methyl 1-[2-(furan-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carboxylate (4), 1-[2-(furan-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carboxylic acid (5), L-pyroglutamic acid (6), L-pyroglutamic acid ethyl ester (7), 3-O-caffeoylquinic acid methyl ester (8), 3-O-caffeoylquinic acid ethyl ester (9), 5-O-caffeoylquinic acid methyl ester (10), 5-O-caffeoylquinic acid ethyl ester (11), 4-O-caffeoylquinic acid methyl ester (12), 4-O-caffeoylquinic acid methyl ester (13), 4-O-caffeoylquinic acid (14), 3-O-caffeoylquinic acid (15), respectively, based on the spectral analysis such as NMR, MS etc. Compounds 1-14 were isolated from this genus for the first time, among which 1 was a new compound.
