Preparation and characteristics of iron oxide nanoparticles modified by bovine serum albumin.
- Author:
Peng ZHAO
1
;
Jie WENG
;
Peng HOU
Author Information
1. Key Laboratory of Materials Advanced Technologies (Ministry of Education), School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Cattle;
Ferrosoferric Oxide;
chemistry;
Magnetics;
Metal Nanoparticles;
chemistry;
Serum Albumin, Bovine;
chemistry
- From:
Journal of Biomedical Engineering
2009;26(5):1005-1009
- CountryChina
- Language:Chinese
-
Abstract:
Ultrafine iron oxide nanoparticles were prepared in aqueous solution using chemical coprecipitation method. Adsorption of bovine serum albumin (BSA) on magnetic particles was studied in the presence of silane coupling KH550. Characterizations of magnetic particles were carried out by X-ray diffraction, Transmission electron microscopy, Fourier transform infrared spectrometer and vibrating-sample magnetometer. The experimental results showed that magnetic nanoparticles were well dispersed with a small decrease of the magnetic saturation after modification. Magnetic nanoparticles wrapped in KH550 were favorable to the adsorption of BSA while the capability of hydrophile increased consequently, which could be used for target carrier in biomedicine.
