Preparation and properties of poly (acrylic ester) hydrogel as basic materials for intraocular lens.
- Author:
Yuzheng XIA
1
;
Hui LIU
;
Shuxian SHI
;
Xiaonong CHEN
;
Shuke JIAO
Author Information
1. The Key Laboratory of Beijing City on Preparation and Processing of Novel Polymer Materials, Material Science and Engineering College, Beijing University of Chemical Technology, Beijing 100029, China.
- Publication Type:Journal Article
- MeSH:
Acrylic Resins;
chemical synthesis;
chemistry;
Biocompatible Materials;
chemical synthesis;
chemistry;
Humans;
Hydrogels;
chemical synthesis;
chemistry;
Lenses, Intraocular;
Polyhydroxyethyl Methacrylate;
chemical synthesis;
chemistry;
Tensile Strength
- From:
Journal of Biomedical Engineering
2009;26(5):1047-1051
- CountryChina
- Language:Chinese
-
Abstract:
Poly (acrylic ester) hydrogel materials were widely used in intraocular lens and contact lens because of their excellent optical performance and biocompatibility. In this paper, the bulk copolymerization behavior of hydrophilic hydroxyethyl methacrylat with hydrophobic methyl metharylate was studied; and the optical performance, calcium deposits, equilibrium water content of polymers and its hydrogels obtained by different ratios of monomers were systematically investigated. The experimental results showed that the average light transmittance and the equilibrium water content of the obtained hydrogels increased with the increasing of the hydrophilic monomer content from 0 to 100%; however, the hardness decreased. The highest light transmittance reached 97% and the hardness of Shore A fell from 92 to 25, the equilibrium water content of hydrogel increased from 16% to 64%. The absorbent capacity of copolymers reduced with the adding of cross-linking monomer. When m(hydrophilic monomer): m(hydrophobic monomer) = 90 : 10, the combination property of the polymer and its hydrogel obtained is optimum.
