Hepatitis B virus infection and the risk of coronary atherosclerosis.
- Author:
Reza GHOTASLOU
1
;
Nasser ASLANABADI
;
Morteza GHOJAZADEH
Author Information
- Publication Type:Journal Article
- MeSH: Child, Preschool; Cholesterol, HDL; blood; Cholesterol, LDL; blood; Cholesterol, VLDL; blood; Coronary Angiography; Coronary Artery Disease; diagnosis; epidemiology; etiology; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Hepatitis B; blood; complications; epidemiology; Hepatitis B Surface Antigens; blood; Hepatitis B virus; immunology; Humans; Incidence; Infant; Iran; epidemiology; Male; Retrospective Studies; Risk Factors; Sex Distribution
- From:Annals of the Academy of Medicine, Singapore 2008;37(11):913-915
- CountrySingapore
- Language:English
-
Abstract:
INTRODUCTIONMany studies have reported on the association between human coronary artery disease (CAD) and certain persistent bacterial and viral infections. Currently, it is unclear whether hepatitis B virus infection is associated with the risk of the atherosclerosis. The aim of this study was to investigate the possible association between hepatitis B virus infection and angiography-proven CAD.
MATERIALS AND METHODSSera from 5,004 patients who underwent coronary angiography were tested for hepatitis B surface antigen (HBsAg) by enzyme-linked immunosorbant assay at Madani Heart Hospital, Tabriz University of Medical Sciences, Iran.
RESULTSOur study population comprised 66% male and 34% female, with an age range of 36 to 86 years. The prevalence of HBsAg positivity tended to be higher in CAD patients than in those without CAD (3.28% versus 2.17%), but the difference was not statistically significant.
CONCLUSIONOur results suggest that hepatitis B virus infection is not associated with coronary atherosclerosis in this population.
