The distribution of serum homocysteine and its associated factors in a population of 1 168 subjects in Beijing area.
- Author:
Wei WANG
1
;
Dong ZHAO
;
Jun LIU
;
Jie LIU
;
Zhenling ZHANG
;
Jing LIU
;
Sa LIU
;
Zheng LIN
;
Zhaosu WU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Age Factors; China; epidemiology; Female; Homocysteine; blood; Humans; Hyperhomocysteinemia; epidemiology; Male; Middle Aged; Risk Factors; Rural Health; statistics & numerical data; Sex Factors; Urban Health; statistics & numerical data
- From: Chinese Journal of Epidemiology 2002;23(1):32-35
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo describe serum homocysteine distribution and its associated factors in population of urban and rural areas in Beijing.
METHODSThe study population was represented by a randomly selected sample with 1 168 subjects, including both males and females aged 35 - 64. The levels of serum homocycteine were compared and the correlation with other risk factors were analyzed statistically.
RESULTS(1) Geometric mean of serum homocycteine was 15.4 micromol/L in males and 12.2 micromol/L in females (P < 0.001). (2) There was a significant difference in homocysteine levels between urban population and rural population. Men from rural area had 1.5 times higher homocyteine than from urban (18.0 micromol/L vs 12.0 micromol/L, P < 0.001), while the rural women had 1.3 times higher homocysteine level than urban women did. (3) The prevalence rate of hyperhomocysteinemia was 15.3% in population aged 35 - 64 in Beijing area. (4) Gender, residential location (urban or rural), smoking and education had independent effects on level of serum homocysteine by multivariate analysis.
CONCLUSIONPopulation in Beijing had higher serum level and prevalence rate of homocysteine than some western countries. Gender, geographic distribution, smoking and education had some influence on homocysteine level.
