Study on the neonate umbilical cord blood thyroid stimulating hormone level in the universal iodized salt areas and its application.

Author: Huijie DONG ¹ ; Qingsi ZHENG
Author Information

1. Department of Iodine Deficiency Disorders, Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100020, China.
Publication Type:Journal Article
MeSH: Delivery, Obstetric; Female; Fetal Blood; drug effects; metabolism; Humans; Iodine; pharmacology; urine; Pregnancy; Thyrotropin; blood
From: Chinese Journal of Epidemiology 2002;23(4):250-253
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo investigate the neonatal umbilical cord blood thyroid stimulating hormone (TSH) level in the universal iodized salt areas and put forward the cut-point, then analyze its application.
METHODSSeven provinces were selected where the pregnant women having satisfied urinary iodine levels, then the urinary samples of pregnant women and the neonates cord blood were collected for urine iodine and TSH tests, and the relative factors were also recorded.
RESULTSTotal 1 524 urine and cord blood samples were collected from pregnant women and their new borns respectively. The median urinary iodine of pregnant women was 246.0 micro g/L, and the median TSH was 3.58 mU/L. The TSH level among seven areas and the neonatal delivery type varied significantly.
CONCLUSIONSThe neonatal cord blood TSH was influenced by several factors and could not be controlled, thus not be suitable as a iodine deficiency disorders surveillance indicator.