Discovery of two sub-types of Hantanvirus in Anhui mountain areas.
- Author:
Zhaozhuang LUO
1
;
Yan LIU
;
Hong LIU
;
Yiyin WANG
;
Yueping ZHAO
Author Information
- Publication Type:Journal Article
- MeSH: Animals; China; Hantaan virus; classification; genetics; Muridae; virology; Rats; Reverse Transcriptase Polymerase Chain Reaction; Serotyping
- From: Chinese Journal of Epidemiology 2002;23(5):363-365
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the existence of hemorrhagic fever with renal syndrome (HFRS) foci in high mountains and forest areas.
METHODSA survey was conducted in the areas of 1 400 meter altitude in Dabie mountain and of 1,600 meter altitude in Wannan mountain in the mid 1990's using methods related to epidemiology, geographic-epidemiology, serum epidemiology, pathogenic and molecular epidemiology.
RESULTSTwo strains of HFRS viruses were isolated from pulmonary tissues of Rattus niviventer and both of them were identified as A types. The analysis of the nuclei sequence showed that there were significant differences between both sub types and HTN 76-118.
CONCLUSIONIt was confirmed that there were HFRS foci in the areas with 2 strains possible new sub-types of HFRS.
