Viable myocardium detecting by CARTO voltage mapping in swine model of acute myocardial infarction
10.3760/cma.j.issn.0253-3758.2010.08.009
- VernacularTitle:CARTO电压标测识别猪急性心肌梗死模型中存活心肌的研究
- Author:
Tao LIN
1
;
Yi-Tong MA
;
Yi-Ning YANG
;
Hu-Yati MU
;
Peng-Yi HE
;
Yu-Chun YANG
;
Ping CHOU
;
Fen LIU
;
Yan-Yi ZHANG
Author Information
1. 新疆医科大学第一附属医院
- Keywords:
Myocardial infarction;
Myocardium;
Cell survival;
Electrophysiologic techniques,cardiac
- From:
Chinese Journal of Cardiology
2010;38(8):716-719
- CountryChina
- Language:Chinese
-
Abstract:
Objectiye To evaluate the accuracy and practicability of detecting viable myocardium by CARTO voltage mapping in swine model of acute myocardial infarction(MI). Methods MI was induced in 13 anesthetized swines via occluding the distal of left anterior descending coronary arteries by angioplasty balloon for 60-90 minutes. The viable myocardium detection by CARTO voltage mapping was made after reconstruction of the left ventricle using CARTO and the results were compared with TTC staining. The standard of CARTO voltage to detect viable myocardium was 0. 5 - 1.5 mV while viable myocardium showed pink color by TTC staining. Results Eleven out of 13 swines survived the operation and 2 swines died of ventricular fibrillation at 45 and 65 minutes post ischemia. Left ventricle was divided into 16 segments and 176 segments from 11 swines were analyzed. Viable myocardium detected by CARTO voltage mapping was identical as identified by TTC staining(Kappa =0. 816,P ＜0. 001). Taken the TTC result as standard, the sensitivity, specificity and accuracy rate of CARTO voltage mapping are 71.8%, 96.5% and 90.9%respectively. Conclusion CARTO voltage mapping could be used as a reliable tool to detect viable myocardium in this model.
