Association between delayed enhancement on cardiac magnetic resonance imaging and arrhythmia in patients with hypertrophic cardiomyopathy.
- Author:
Jing WANG
1
;
Xiang-quan KONG
;
Hai-bo XU
;
Guo-feng ZHOU
;
Fang LIU
;
Hao-jun SHI
;
Ding-xi LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Arrhythmias, Cardiac; etiology; Cardiomyopathy, Hypertrophic; complications; pathology; physiopathology; Female; Humans; Magnetic Resonance Imaging; methods; Male; Middle Aged; Young Adult
- From: Chinese Journal of Cardiology 2010;38(9):775-780
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEto observe the association between myocardial fibrosis, detected by delayed-enhancement (DE) cardiac magnetic resonance imaging (MRI) and arrhythmia in patients with hypertrophic cardiomyopathy (HCM).
METHODSforty-eight untreated HCM patients who underwent Cine MR, DE-MRI, 24 h ambulatory Holter electrocardiogram and ECG examinations were recruited. Extent of myocardial fibrosis (fibrosis mass/total LV mass) was assessed using DE imaging. Association between arrhythmias including premature ventricular complexes (PVCS ≥ 200), supra-ventricular tachycardia (SVT), non-sustained ventricular tachycardia (NSVT), atrio-ventricular block (AVB) and intra-ventricular block (IVB) detected by Holter monitoring and ECG with regard to delayed enhancement (DE) on contrast enhanced CMR was analyzed.
RESULTSmyocardial fibrosis was detected in 35 patients. Incidence of arrhythmia was significantly higher in patients with DE than in patients without DE (P < 0.05). Extent of myocardial fibrosis was significantly associated with the QRS duration (r = 0.33, P < 0.001).
CONCLUSIONmyocardial fibrosis detected by DE-CMR was associated with arrhythmia in patients with HCM. DE-CMR might be helpful to detect high-risk HCM patients prone to arrhythmia.
