Early repolarization syndrome and recurrent syncope in two Chinese pedigrees
10.3760/cma.j.issn.0253-3758.2010.09.010
- VernacularTitle:早期复极综合征并反复晕厥两家系报告
- Author:
Zhen-Ni TAN
1
;
Wei DENG
;
Yuan-Yuan LUO
;
Heng LI
;
Shao-Xi SUN
;
Su-Rong MENG
;
Ding-Li XU
;
Jian PENG
Author Information
1. 南方医科大学附属南方医院
- Keywords:
Syncope;
Tachycardia,ventricular;
Ventricular fibrillation;
Early repolarization syndrome
- From:
Chinese Journal of Cardiology
2010;38(9):801-804
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characteristics in two families with early repolarization syndrome(ERS) and recurrent syncope. Method All family members including the probands were screened with routine clinical examination, electrocardiography, echocardiography, Holter recording,chest x-ray, head-up tilt test and blood biochemistry. Results There was no clinical evidence of organic heart disease in all members from the two families. Proband 1 showed recurrent syncope, ERS and repeated torsade de pointes ventricular tachycardia and ventricular fibrillation were documented with resting ECG.ERS was detected in one brother, one nephew and one son from him and all were free of cardiac events including syncope, cardiac arrest and sudden cardiac death. Proband 2 showed recurrent syncope, ERS and ST segment arched upward elevation in V1 - V3 were documented by ECG. His father suffered sudden cardiac death at the age of 65 and asymptomatic ERS was detected in one of his nephew. Conclusions ERS is not always linked with benign clinical course and can sometimes lead to repeated synocope, torsade de pointes ventricular tachycardia and ventricular fibrillation. Pedigree research is of importance for ERS.
