Clinical features and prognosis of 188 Chinese patients with apical hypertrophic cardiomyopathy.
- Author:
Yong-kang TAO
1
;
Li-rong YAN
;
Yi-shi LI
;
Zhi-min XU
;
Guo-qiang ZHANG
;
Li-mei ZU
;
Hai-yan DU
;
Chao-mei FAN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Cardiomyopathy, Hypertrophic; diagnosis; epidemiology; Female; Humans; Male; Middle Aged; Prognosis; Retrospective Studies; Young Adult
- From: Chinese Journal of Cardiology 2011;39(2):106-109
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the clinical characteristics and prognosis of Chinese patients with apical hypertrophic cardiomyopathy (AHCM).
METHODSA total of 188 patients with AHCM diagnosed at Fuwai Hospital were included in this retrospective study. Clinical characteristics, mortality and cardiovascular morbidity were analyzed. A multiple logistic regression was performed to adjust for potential confounding factors.
RESULTSMales predominated with a number of 139 (73.9%) in this cohort. Patient's age ranged from 15 to 81 (51.9 ± 12.6) years. There were 120 patients (63.8%) with "pure" type and 68 patients (36.2%) with "mixed" type of AHCM, 171 patients were followed up for (5.0 ± 3.0) years, cardiovascular mortality was 1.2%, 28 patients (16.4%) experienced one or more cardiovascular events.
CONCLUSIONThe prevalence of AHCM is high in Chinese HCM patients, pure type AHCM is more common, and AHCM patients have a benign clinical course.