Clinical characteristics of fat replacement of left ventricular myocardium
10.3760/cma.j.issn.0253-3758.2011.02.014
- VernacularTitle:左心室心肌脂肪替代的临床特征及意义
- Author:
Chao-Wu YAN
1
;
Shi-Hua ZHAO
;
Hua LI
;
Shi-Liang JIANG
;
Jian LING
;
Yan ZHANG
;
Bin L(U)
;
Min-Jie LU
;
Yun-Qing WEI
;
Cheng CAO
;
Xiao-Ou QI
;
Min-Fu YANG
;
Wei FANG
Author Information
1. 中国医学科学院北京协和医学院阜外心血管病医院
- Keywords:
Tomography,X-ray computed;
Myocardial infarction;
Fat replacement
- From:
Chinese Journal of Cardiology
2011;39(2):152-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical characteristics of left ventricular fat replacement. Methods We identified 45 patients [28M/17F, mean age (51.9 ± 14. 7 )years] with left ventricular myocardial fat replacement ( CT value ≤ - 30 Hu) by cardiovascular CT. Results Among 45 patients, 25 patients[20M/5F, mean age (61.2 ± 10. 4) years] were diagnosed as coronary artery disease (CAD). There was 56% single-vessel disease, 20% double-vessel disease and 24% triple-vessel disease,true left ventricular aneurysm was detected in 3 patients and left ventricular thrombi in 1 patient, the dimension of left ventricle was (54. 5 ±9. 4) mm and the LVEF was (51.8 ± 13 ) % in CAD group. In this group, fat replacement occurred in the region of myocardial infarction and presented as curvilinear band in subendocardial region. The left ventricular wall thickness was lower than 5 mm in 21 cases. The location of fat replacement in CAD group is as follows: apical region in 18 patients, distal septal in 15 patients, distal anterior in 11 patients, mid-septal in 7 patients, mid-anterior in 7 patients and basal in 1 patients. The age of remaining 20 patients (8M/12F) without CAD were (57. 8 ± 13.3) years. In the group of non-CAD,dilated cardiomyopathy was diagnosed in 3 patients, atrial septal defect in 1 patient, rheumatic heart disease in 1 patient, there was no structural heart disease in the remaining 15 patients. The dimension of left ventricle was (51.1 ± 9. 1 ) mm and the LVEF was (59. 4 ± 13.9 )%. In non-CAD group, fat replacement mainly occurred in septal region, presented as curvilinear band in 17 patients and patch in 3 patients. The location of fat replacement in this group is as follows: mid-septal region in 11 patients, distal-septal in 10 patients and apical in 9 patients. The intramural fat replacement was detected in 14 patients: subendocardial fat replacement in 10 patients and both intramural and subendocardial fat replacement in 4 patients. Conclusions Left ventricular fat replacement could be documented in CAD patients, non-CAD cardiomypathy patients and in patients without structural heart disease. Left ventricular fat replacement often positioned in apical region in CAD patients as a consequence of infarct healing while mostly positioned in septal region in non-CAD patients, the definite clinical implication of left ventricular fat replacement in nonCAD patients remains to be clarified.
