- Author:
Ja Kyung JUN
1
;
Cheong Jun MOON
;
Soon Ju KIM
;
Young Ah YOUN
;
Ju Young LEE
;
Hyun Seung LEE
;
Jung Hyun LEE
;
In Kyung SUNG
;
So Young KIM
Author Information
- Publication Type:Original Article
- Keywords: Electrolytes; Extremely-low-birth-weight infant; Humidity; Insensible water loss
- MeSH: Apnea; Electrolytes; Humans; Humidity; Hypernatremia; Infant; Infant, Newborn; Infant, Premature; Intensive Care, Neonatal; Medical Records; Retrospective Studies; Seizures; Skin; Sodium; Survival Rate; Water Loss, Insensible; Water-Electrolyte Balance
- From:Neonatal Medicine 2013;20(1):106-112
- CountryRepublic of Korea
- Language:Korean
- Abstract: PURPOSE: Extremely-low-birth-weight infants (ELBWIs), especially those < or =24 gestational weeks (GW), presented extremes in IWL and changes of water balance. The purpose of the present study was to retrospectively investigate fluid and electrolyte balance in infants of < or =24-GW during the first postnatal week under high humidification. METHODS: Medical records of extremely-low-birth-weight infants (ELBWIs) who were born and admitted to the Neonatal Intensive Care Unit at Samsung Medical Center during March 2004-September 2010 were reviewed. Fluid intake, urine output, insensible water loss (IWL), and electrolyte balance of 22-GW (n=14), 23-GW (n=40), and 24-GW (n=67) infants nursed in high humidity (95%) were compared with > or =26-GW (n=65) infants nursed in 60% humidity. RESULTS: Survival rate until discharge was 33%, 82%, 75%, and 89.3% in 22-GW, 23-GW, 24-GW, and > or =26-GW infants, respectively. Fluid intake and IWL was higher in 22-GW and 23-WG, but not different in 24-GW, than in > or =26-GW infants. At postnatal days (P) 3-5, the urine output was significantly lower in > or =26-GW infants than in the other age groups. Serum sodium level was significantly higher in 22-, 23-, and 24-GW (P1-2) than in > or =26-GW infants. Hypernatremia (>150 mEq/dl sodium) was more frequent in 22-GW (71%), 23-GW (41%), and 24-GW (21%) than in > or =26-GW infants (14%). CONCLUSION: High-humidity environments significantly decreased fluid intake and improved electrolyte imbalance in 24-GW, but not 22- and 23-GW, infants. Increased IWL in the latter might be related to more immature skin, and implicates the need for additional nurturing conditions.