Psychological stress status in patients with acute coronary syndrome and stable angina pectoris
10.3321/j.issn:0253-3758.2008.03.006
- VernacularTitle:心理应激与急性冠状动脉综合征
- Author:
Mu-Wei LI
1
;
Lei YANG
;
Chuan-Yu GAO
;
Yu-Xiang SHEN
;
Ye-Xin MA
Author Information
1. 河南省人民医院
- Keywords:
Coronary disease;
Stress,psychology;
Inflammatory factors
- From:
Chinese Journal of Cardiology
2008;36(3):212-214
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the psychological stress status in patients with acute coronarysyndrome(ACS)and stable angina pectoris(SA).Methods The intensity of social psychological stress and the Serum levels of IL-6,CRP and ICAM-1 were determined in patients with ACS(n=67)and SA (n=33).Results(1)The percentage of patients with psychological stress was significantly higher in ACS than that in SA group(78.8% vs.21.2%,P＜0.01).(2)The serum levels of CRP[(14.82±5.07)g/L vs.(8.78±4.34)g/L],IL-6[(101.7±22.2)ng/L vs.(71.1±23.5)ng/L]and sICAM-1[(1.41±0.47)mg/L vs.(0.82±0.37)mg/L]were significantly higher in psychological stress group than those in non-psychological stress group(all P＜0.05).Serm CRP[(18.91±3.12)g/L vs.(6.20±2.46)g/L],IL-6[(114.6±15.2)ng/L vs.(56.4±15.8)ng/L]and sICAM-1[(1.67±0.39)mg/L vs.(0.63±0.28)mg/L]levels in ACS group were significantly higher than those in SA group(all P＜0.01).Conclusion Higher psychological stress was associated with higher risk of ACS and increased serum inflammatory cytokines.
