Primary risk factors in Chinese patients with first acute myocardial infarction
10.3321/j.issn:0253-3758.2008.07.002
- VernacularTitle:初发急性心肌梗死发病危险因素分析
- Author:
Dong WU
1
;
Qi HUA
;
San-Qing JIA
;
Zhan-Quan LI
;
Xiu-Li ZHAO
;
Ying-Xian SUN
;
Da-Yi HU
Author Information
1. 首都医科大学附属北京同仁医院
- Keywords:
Acute myocardial infarction;
Risk factors;
Matched case-control study
- From:
Chinese Journal of Cardiology
2008;36(7):581-585
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the primary risk factors of patients with first ST elevation acute myocardial infarction(FSTEMI) in Beijing and Shenyang area between 2004 -2005. The Attributable risk percentage (ARP) and population attributable risk percentage (PARP) of every risk factor were determined. Method A total of 426 consecutive FSTEMI patients and 426 gender and age matched healthy controls were included in this 1:1 matched case-control study. Result Multivariate logistic regression analysis showed that following 8 primary risk factors were associated with FSTEMI : heavy smoking ( OR = 3. 170), diabetes (OR =2.835), positive family history (OR =2.243), lack of soybeans intake (OR = 2. 243), higher psychological stress ( OR = 2. 138 ), lack of fish intake ( OR = 1. 740), lower education level (OR = 1. 572) and recent adverse life events ( < 6 months before FSTEMI, OR = 1. 515). The ARP are 71.53% ,58.33% ,54. 05% ,40. 81% ,56. 85% ,41.53% ,48. 62% ,54. 00% ;the PARP are 38.79%, 10. 40%, 4. 69%, 33. 72%, 36. 03%, 24. 96%, 29. 56%, 14. 83%, respectively. Conclusion In this patient cohort, the harmful risk factors responsible for the development of FSTEMI in Beijing and Shenyang areas during 2004- 2005 are heavy smoking, higher psychological stress, lack of soybeans intake, lower education level, lack of fish intake, recent adverse life events, diabetes and positive family history.