Impact of admission heart rate on in-hospital mortality in patients with acute myocardial infarction
10.3321/j.issn:0253-3758.2008.07.005
- VernacularTitle:心率对急性心肌梗死患者住院期间病死率的影响
- Author:
Chun-Mei WANG
1
;
Xue-Si WU
;
Zhi-Hong HAN
;
Qian ZHANG
Author Information
1. 首都医科大学附属北京安贞医院
- Keywords:
Myocardial infarction;
Heart rate;
Prognosis
- From:
Chinese Journal of Cardiology
2008;36(7):594-597
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the impact of admission heart rate (HR) on in-hospital mortality in patients with acute myocardial infarction.Method The data of 904 in-hospital patients with ST-elevation myocardial infarction were collected from database of Beijing Anzhen Hospital during 2003-2004.The patients were divided into three groups according to the admission HR: < 80 beats/min,80-90 beats/min and > 90 beats/min.Lett ventricular ejection fraction (LVEF), left ventricular end diastolic dimension (LVEDD), left ventricular end systolic dimension (LVESD) and the cases of in-hospital death were analyzed.Result (1) Age, gender, smoking, hypertension, diabetes, the number of diseased vessel detected by coronary angiography were similar among three groups.LVEDD in group >90 beats/min [ (51.9 ± 7.5)mm] and group 80-90 beats/min [ (51.6±5.8)mm] were significantly larger compared with group < 80 beats/min [ (50.3 ± 5.3) mm, all P < 0.05 ] ; LVESD in group > 90 beats/min [ (39.5 ± 8.7 ) mm ] were also significantly increased compared with group 80-90 beats/min [ ( 37.1 ± 7.1 ) mm] and group < 80 beats/min [ (34.8 ± 6.2 ) mm, all P < 0.05 ] ; LVEF was significantly lower in group > 90 beats/min (46.0% ± 10.6% ) compared with group 80-90 beats/min(49.5% ± 11.3% ) and group < 80 beats/min (54.6%±10.8%, all P <0.05).In-hospital mortality was significantly higher in group >90 beats/min ( 18.2% ) than those in group 80-90 beats/min and in group < 80 beats/min ( 8.5%, 3.9% , all P < 0.05).(2) Multivariate analysis showed that admission HR was an independent risk factor for in-hospital mortality ( OR = 1.025,95 % CI 1.008-1.043, P = 0.005 ).conclusion The high level of admission HR was a powerful predictor of in-hospital mortality and ventricular remolding in patients with acute myocardial infarction.
