Progress in microbial production of prodigiosin.

Author: Zhongyu YOU ¹ ; Yujie WANG ¹ ; Shiqing SUN ¹ ; Xiaoxia LIU ¹
Author Information

1. College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001, Zhejiang, China.
Publication Type:Journal Article
Keywords: fermentation; optimization and regulation; prodigiosin; strain breeding; synthesis pathway; transcriptional regulation
From: Chinese Journal of Biotechnology 2016;32(10):1332-1347
CountryChina
Language:Chinese
Abstract: Prodigiosin is an important natural red pigment that is produced as a secondary metabolite by microorganisms, and has great potential applications in the field of pharmaceutical development, environmental management and dye preparation. This paper reviews recent research progress in the production of prodigiosin by microbial fermentation, including discovery and modification of the prodigiosin-producing microorganisms, regulation and optimization of prodigiosin fermentation and extraction process, and resolution of biosynthetic pathway of prodigiosin and related transcriptional regulation. Finally, we discussed the future research directions in microbial production of prodigiosin.