The Significance of Gastroesophageal Reflux Disease (GERD) Symptoms in Patients with Reflux Esophagitis.
- Author:
Chan Hee HAN
1
;
Joon Seong LEE
;
Hee Hyuk LIM
;
Young Soo OH
;
Young Keun YOON
;
Sang Gyune KIM
;
Myung Soo KIM
;
Eun Sang RYOO
;
Dong Jin YOUN
;
In Seop JUNG
;
Bong Min KO
;
Chang Bum YOO
;
Young Deok CHO
;
Joo Young CHO
;
Moon Sung LEE
;
Chan Sup SHIM
Author Information
1. Department of Internal Medicine, Soon Chun Hyang University College of Medicine, Seoul, Korea. schidr@hosp.sch.ac.kr
- Publication Type:Original Article
- Keywords:
Gastroesophageal reflux disease;
Reflux esophagitis;
Esophageal sensitivity;
24 hr ambulatory esophageal pH monitoring
- MeSH:
Endoscopy;
Esophageal pH Monitoring;
Esophagitis;
Esophagitis, Peptic*;
Gastroesophageal Reflux*;
Hernia, Hiatal;
Humans;
Hydrogen-Ion Concentration;
Manometry;
Perfusion;
Surveys and Questionnaires
- From:Korean Journal of Gastrointestinal Motility
2000;6(2):196-205
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: The relationship between the symptoms and severity of GERD may be difficult to prove. The intensity and frequency of reflux induced symptoms are poor predictors of the presence or severity of an endoscopic mucosal break. The aim of this study was to determine which factors can be predicted by the presence of GERD symptoms among esophageal sensitivity to acid, abnormal acid reflux, and severity of esophagitis in pateints with reflux esophagitis. METHODS: Fourty-four patients who were diagnosed with reflux esophagitis by an endoscopy at a tertiary medical facility, were given a validated questionnaire, and underwent an acid perfusion test, 24 hr ambulatory esophageal pH monitoring, and esophageal manometry. These patients were divided into a symptomatic group and asymptomatic group according to the questionaire. Comparisons between the two groups for each factor were analyzed by Chi-square. RESULT: Of 44 patients, 26 had symptoms and 18 did not. The positive and equivocal rates of the acid perfusion test were not different between the symptomatic and asymptomatic groups (47% vs. 39%). The abnormal reflux rate (DeMeester score > 14.72) from pH monitoring was significantly higher in the symptomatic group than in the asymptomatic group (65% vs. 28%, p < 0.05). The severity of esophagitis, presence of a hiatal hernia, and abnormal esophageal manometric findings were not different between the two groups. CONCLUSION: It would be impossible to predict esophageal sensitivity to acid, severity of the esophagitis grade, and the presence of hiatal hernia with GERD symptoms, but it could be possible to predict abnormal gastroesophageal reflux.
