Advances in isoprene synthase research.

Author: Yan GOU ¹ ; Zhongchuan LIU ¹ ; Ganggang WANG ¹
Author Information

1. Key Laboratory of Environmental and Applied Microbiology of Chinese Academy of Sciences, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, Sichuan, China.
Publication Type:Journal Article
Keywords: biochemical characteristics; catalytic mechanism; isoprene; isoprene synthase; structure features
From: Chinese Journal of Biotechnology 2017;33(11):1802-1813
CountryChina
Language:Chinese
Abstract: Isoprene emission can lead to significant consequence for atmospheric chemistry. In addition, isoprene is a chemical compound for various industrial applications. In the organisms, isoprene is produced by isoprene synthase that eliminates the pyrophosphate from the dimethylallyl diphosphate. As a key enzyme of isoprene formation, isoprene synthase plays an important role in the process of natural emission and artificial synthesis of isoprene. So far, isoprene synthase has been found in various plants. Isoprene synthases from different sources are of conservative structural and similar biochemical properties. In this review, the biochemical and structural characteristics of isoprene synthases from different sources were compared, the catalytic mechanism of isoprene synthase was discussed, and the perspective application of the enzyme in bioengineering was proposed.