Prevalence and risk factors of peripheral arterial disease in diabetic patients over 50 years old in China.
- Author:
Heng GUAN
1
;
Yong-Jun LI
;
Zhang-Rong XU
;
Guang-Wei LI
;
Xiao-Hui GUO
;
Zhi-Min LIU
;
Da-Jin ZOU
;
Hui-Li XING
;
Wei LIU
;
Zheng-Yan SHENG
;
Hao-Ming TIAN
;
Da-Long ZHU
;
De-Min YU
;
Wei-Te ZHUANG
;
Lu-Lu CHEN
;
Jian-Ping WENG
Author Information
- Publication Type:Journal Article
- MeSH: Aged; China; epidemiology; Diabetic Angiopathies; epidemiology; Female; Humans; Male; Middle Aged; Peripheral Vascular Diseases; epidemiology; Prevalence; Risk Factors; Urban Population; statistics & numerical data
- From: Chinese Medical Sciences Journal 2007;22(2):83-88
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo investigate the prevalence of peripheral arterial disease (PAD) in China type 2 diabetic patients and to demonstrate the relationships between putative risk factors and PAD.
METHODSIn total 1,397 type 2 diabetic patients aged 50 years and older were enrolled and determined ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) in 15 Class III Grade A hospitals in 7 major cities of China.
RESULTSMean patient age was 63.7 +/- 8.2 years and mean duration of diabetes mellitus was 9.39 +/- 7.4 years. Two hundreds and seventy-two (19.47%) patients were diagnosed as PAD by ABI < 0.9, 122 (18.37%) in male and 150 (20.46%) in female. PAD patients had a significantly longer duration of diabetes mellitus, higher hemoglobin A1c, and a significantly lower mean body mass index than non-PAD ones. Aging, smoking, and systolic blood pressure were found to be positively related with the prevalence of PAD. In terms of lipid profiles, no variable was found to relate with PAD. Notably, baPWV showed as the same significant guiding index for PAD, almost matched with ABI.
CONCLUSIONSPAD is a common complication in China type 2 diabetic patients. Therefore, PAD screening and treatment should be emphasized for diabetic patients with high risk factors.
