Pathophysiological changes in mitochondria of mammalian exposed to hypoxia at high altitude.
- Author:
Wen-xiang GAO
;
Gang WU
;
Yu-qi GAO
- Publication Type:Journal Article
- MeSH:
Adaptation, Physiological;
Altitude;
Altitude Sickness;
Animals;
Humans;
Hypoxia;
Mitochondria;
pathology;
Oxygen;
physiology
- From:
Chinese Journal of Applied Physiology
2014;30(6):502-505
- CountryChina
- Language:Chinese
-
Abstract:
As human beings ascend to high altitude, a number of reactions may occur against hypoxic injuries. These hypoxic responses are related to intake, transportation and utility of the oxygen. As a crucial subcellular organelle of oxygen utility, mitochondrion is a central link of high altitude acclimatization, adaptation and mountain sicknesses. In this review, we discussed the recent advances in researches on hypoxic mitochondrial responses at high altitude.
