Two Cases of Glaucoma Developed during Induction Chemotherapy Including Steroid in Childhood Acute Lymphoblastic Leukemia.
- Author:
Jung Sig MOON
1
;
Jung Il MOON
;
Hyun Jung LEE
;
Bin CHO
;
Hack Ki KIM
;
Kyong Su LEE
Author Information
1. Department of Ophthalmology, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Glaucoma;
Leukemia;
Steroid
- MeSH:
Adrenal Cortex Hormones;
Carbonic Anhydrases;
Child;
Drug Therapy;
Glaucoma*;
Humans;
Incidence;
Induction Chemotherapy*;
Intraocular Pressure;
Leukemia;
Ocular Hypertension;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
- From:Korean Journal of Pediatric Hematology-Oncology
1999;6(1):151-155
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of the study is to minimize the incidence of glaucoma and ocular hypertension caused by using corticosteroids during induction chemotherapy for acute lymphoblastic leukemia in children. We have periodically observed the intraocular pressure and the variation of C / D ratio of two 7 years old boys with chemotherapy in our pediatric department. We observed the increase in intraocular pressure using applanation tonometer, and we managed by beta- blockers, carbonic anhydrase inhibitor and etc. Increased intraocular pressure has been normalized after chemotherapy. The frequency of occurrence of the ocular hypertension and glaucoma can be controlled with the quantity of corticosteroids used.
