Comparative study on the ability of adhesion and invasion of different fimA genetypes of Porphyromonas gingivalis to oral epithelial cells

VernacularTitle:不同fimA基因型牙龈卟啉单胞菌黏附和侵入口腔上皮细胞能力的比较
Author: Li GAO ¹ ; Ya-Fei WU ; Di MIAO ; Lei ZHAO ; Shu MENG ; Jie WANG
Author Information

1. 四川大学华西口腔医学院
Keywords: Porphyromonas gingivalis,Epithelial cells; Bacterial adhesion; fimA genotype
From: Chinese Journal of Stomatology 2010;45(6):342-345
CountryChina
Language:Chinese
Abstract: Objective To compare the ability of adhesion and invasion to epithelial cells by Porphyromonas gingivalis ( Pg) strains with different fimA separated from Chinese. Methods Cultured method and antibiotic protection method were used to determine the adhesive and invasive ability of Pg with different fimA genetypes. The adhesion was observed by scanning electron microscope. Results All the strains adhered and invaded to KB cells, and the adhesion rate ranged from 0.523% to 37. 125% and invasive rate from 0. 017% to 3. 750%. The adhesive and invasive ability among different fimA genotypes showed no significant difference (P >0. 05).Conclusions There is no significant correlation between fimA genotype and ability in adhesion and invasion to KB cells.