Castleman Disease Presenting with Jaundice: A Case with the Multicentric Hyaline Vascular Variant.
10.3904/kjim.2007.22.2.113
- Author:
Jun Bean PARK
1
;
Jin Hyeok HWANG
;
Haeryoung KIM
;
Hyung Sim CHOE
;
Yu Kyeong KIM
;
Hong Bin KIM
;
Soo Mee BANG
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine1, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Lymphoproliferative Disorder;
Jaundice;
Obstructive;
Castleman Disease
- MeSH:
Abdominal Pain/etiology;
Adrenal Cortex Hormones/therapeutic use;
Biopsy;
Giant Lymph Node Hyperplasia/*diagnosis/drug therapy/pathology;
Humans;
Jaundice/*complications;
Male;
Middle Aged;
Positron-Emission Tomography;
Tomography, X-Ray Computed;
Vascular Diseases/*diagnosis/pathology
- From:The Korean Journal of Internal Medicine
2007;22(2):113-117
- CountryRepublic of Korea
- Language:English
-
Abstract:
Castleman disease (CD) is a rare lymphoproliferative disorder of unknown etiology with different clinical manifestations. A previous healthy 50 year-old man was hospitalized for right upper quadrant (RUQ) abdominal pain. He had jaundice and a 1 cm-sized lymph node in the right supraclavicular area. Pancreas and biliary computed tomography (CT) showed masses at the right renal hilum and peripancreatic areas. Positron emission tomography (PET) showed widespread systemic lymphadenopathy. Excisional biopsy of the right supraclavicular node revealed a hyaline vascular variant of CD. Corticosteroid therapy was started and the extent of disease decreased. We here report a case of multicentric CD, the hyaline vascular variant, presenting with jaundice, diagnosed by excisional biopsy and successfully treated with corticosteroids.
