Influence factors for prognosis in patients with acute oral poisoning with paraquat.
- Author:
Jing-yan LIU
1
;
Lan-rong LI
;
Hui-yan JIN
;
Gui-fang WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Blood Urea Nitrogen; Creatinine; blood; Female; Humans; Lung Injury; diagnosis; Male; Middle Aged; Multiple Organ Failure; diagnosis; Paraquat; poisoning; Prognosis; Retrospective Studies; Young Adult
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2012;30(9):686-687
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the influential factors for the prognosis in patients with paraquat poisoning.
METHODSRetrospective analysis was performed on 40 patients with acute paraquat poisoning to evaluate serum urea nitrogen, creatinine, alanine aminotransferase, and aspartate aminotransferase levels and organ injuries.
RESULTSAmong the patients, 21 had lung injury, 26 had kidney injury, 13 had multiple organ dysfunction syndrome, and 12 died. The factors associated with lung injury were kidney injury and serum urea nitrogen and creatinine levels within 24 hours after paraquat poisoning.
CONCLUSIONThe renal function in early stage of paraquat poisoning is related to lung injury and thus can be used asa predictor for the incidence of lung injury.