Seroepidemiologic survey of hepatitis G virus in selected population of Shanxi, Qinghai and Xinjiang Provinces (region) of China.
- Author:
Maokai CAO
1
;
Fuping LIU
;
Shuangying JIANG
;
Xiru SHAO
;
Kexue LAN
;
Xinlan LI
;
Zhenxue ZHANG
;
Wen WANG
;
Wenmig ZHAO
;
Ruihua HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Antibodies, Viral; blood; Blood Donors; China; epidemiology; Enzyme-Linked Immunosorbent Assay; Flaviviridae Infections; epidemiology; transmission; GB virus C; immunology; Hepatitis, Viral, Human; epidemiology; transmission; Humans; Immunoglobulin G; blood; Seroepidemiologic Studies; Substance-Related Disorders; virology
- From: Chinese Journal of Experimental and Clinical Virology 2002;16(4):345-347
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the serological features of hepatitis G virus (HGV or GBV) in selected population of Shaanxi, Qinghai and Xinjiang Provinces (region).
METHODSEnzyme-linked immunosorbent assay (ELISA) was used to determine IgG antibody against GBV (anti-GBV IgG) in serum specimens of 1469 individuals from the 3 provinces (region).
RESULTSThe positivity rate of serum GBV-IgG antibody in ethnic minorities (4.11% in Tibetan, 5.36% in Mongolian, 4.55% in Uigur, 4.00% in Hui population) was slightly higher than that in Han population (1.36%-1.73%), but the differences were not significant (P>0.05). The positivity rate of serum GBV-IgG antibody in drug abusers (11.30%, 34/301) was remarkably higher than that of the normal population (2.44%,18/736) (P<0.01). The positivity rate of serum GBV-IgG antibody in blood donors was 1.02%-7.68%.
CONCLUSIONSThe positivity rates of serum GBV-IgG antibody among ethnic groups in the 3 provinces (region) had no significant differences; blood-borne transmission seemed to be an important transmission route of GBV, therefore supervision of blood donors and drug abusers should be intensified.
