Engineering photosynthetic cyanobacterial chassis: a review.
- Author:
Qin WU
;
Lei CHEN
;
Jiangxin WANG
;
Weiwen ZHANG
- Publication Type:Journal Article
- MeSH:
Biofuels;
Cyanobacteria;
genetics;
physiology;
Genetic Engineering;
methods;
Photosynthesis;
Synthetic Biology;
methods
- From:
Chinese Journal of Biotechnology
2013;29(8):1086-1099
- CountryChina
- Language:Chinese
-
Abstract:
Photosynthetic cyanobacteria possess a series of good properties, such as their abilities to capture solar energy for CO2 fixation, low nutritional requirements for growth, high growth rate, and relatively simple genetic background. Due to the high oil price and increased concern of the global warming in recent years, cyanobacteria have attracted widespread attention because they can serve as an 'autotrophic microbial factory' for producing renewable biofuels and fine chemicals directly from CO2. Particularly, significant progress has been made in applying synthetic biology techniques and strategies to construct and optimize cyanobacteria chassis. In this article, we critically summarized recent advances in developing new methods to optimize cyanobacteria chassis, improving cyanobacteria photosynthetic efficiency, and in constructing cyanobacteria chassis tolerant to products or environmental stresses. In addition, various industrial applications of cyanobacteria chassis are also discussed.
