Design and construction of artificial biological systems for complex natural products biosynthesis.
- Author:
Jianfeng WANG
1
;
Hailin MENG
1
;
Zhiqiang XIONG
1
;
Yong WANG
1
Author Information
1. Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China.
- Publication Type:Journal Article
- MeSH:
Biological Products;
chemistry;
metabolism;
Escherichia coli;
genetics;
metabolism;
Neural Networks (Computer);
Recombinant Proteins;
biosynthesis;
genetics;
Synthetic Biology;
methods;
Systems Biology;
methods
- From:
Chinese Journal of Biotechnology
2013;29(8):1146-1160
- CountryChina
- Language:Chinese
-
Abstract:
Natural products (NPs) are important drug pools for human disease prevention and treatment. The great advances in synthetic biology have greatly revolutionized the strategies of NPs development and production. This review entitled with design and construction of artificial biological systems for complex NPs biosynthesis, mainly introduced the progresses in artificial design of synthetic biological parts, naturally mining novel synthetic parts of NPs, the assembly & adaption of the artificial biological modules & systems.
