Cavins: new sights of caveolae-associated protein.
- Author:
Dan SHI
;
Yan LIU
;
Xin LIAN
;
Wei ZOU
- Publication Type:Journal Article
- MeSH:
Animals;
Caveolae;
physiology;
Caveolin 1;
metabolism;
physiology;
Caveolins;
metabolism;
physiology;
Humans;
Membrane Proteins;
metabolism;
physiology;
RNA-Binding Proteins;
metabolism;
physiology
- From:
Chinese Journal of Biotechnology
2013;29(11):1531-1537
- CountryChina
- Language:Chinese
-
Abstract:
Caveolae are specialized lipid rafts that form flask-shaped invaginations of the plasma membrane. Many researches show that caveolae are involved in cell signaling and transport. Caveolin-1 is the major coat protein essential for the formation of caveolae. Recently, several reports indicated that the other caveolae-associated proteins, Cavins, are required for caveola formation and organization. It's worth noting that Cavin-1 could cooperate with Caveolin-1 to accommodate the structural integrity and function of caveolae. Here, we reviewed that the relationship between Cavins and Caveolins and explore the role of them in regulating caveolae.
