CIinical study on treatment of Leber hereditary optic neuropathy.
- Author:
Cheng-wu LI
1
;
Zeng-yuan ZHUANG
;
Shou-kang ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Drugs, Chinese Herbal; therapeutic use; Evoked Potentials, Visual; Female; Humans; Male; Optic Atrophy, Hereditary, Leber; drug therapy; genetics; Phytotherapy; Ubiquinone; analogs & derivatives; therapeutic use; Visual Acuity; Young Adult
- From: Chinese Journal of Integrated Traditional and Western Medicine 2009;29(12):1078-1080
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effect of Wuzi Yanzong Decoction (WYD) in treating Leber hereditary optic neuropathy (LHON).
METHODSThirty patients of LHON up to the requirement were assigned to two groups, the treated group administered with WYD plus coenzyme Q10, and the control group with coenzyme Q10 alone, all for 3 months. Patients' visual acuity, visual field, vision evoked potential (VEP) and their Chinese medicine syndrome were observed before and after treatment.
RESULTSAfter treatment, all the above-mentioned indexes were improved to some extents in the treated group, but showed no evident change in the control group excepting visual acuity, comparison between groups showed the differences were significant in all items.
CONCLUSIONWYD shows certain clinical therapeutic effect for treatment of LHON.
