A prospective follow-up study on the impact of urinary excretions of nickel and chromium after dental restoration by nickel-chromium based alloys.
- Author:
Xinming CAO
1
;
Jue WANG
;
Gang XIA
;
Biyao XU
;
Qingping SHEN
;
Qun ZHONG
;
Qingwu JIANG
;
Bo CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Chromium; Chromium Alloys; Dental Porcelain; Female; Follow-Up Studies; Humans; Male; Nickel; Prospective Studies
- From: West China Journal of Stomatology 2012;30(2):165-168
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore whether the dental restoration of nickel-chromium (Ni-Cr) based alloys will lead to extra excretions of urinary Ni and Cr.
METHODSUrinary Ni and Cr were repeatedly measured in 33 patients before and 2 months after the dental restoration of Ni-Cr alloys. The associations between alloy restoration and urinary Ni or Cr were analyzed by paired t test and general linear model of repeated measures.
RESULTSA slightly higher urinary Ni was found in patients after 2 month of the alloy restoration, but the difference was not statistically significant (before: 46.4 microg x mol(-1) crea; after: 67.6 microg x mol(-1) crea; P=0.063). This difference was only in female subjects (before: 44.8 microg x mol(-1) crea; after: 73.7 microg x mol(-1) crea; P=0.068). A significant higher urinary Cr was found in patients after 2 month of the alloy restoration (before: 57.0 microg x mol(-1) crea; after: 99.4 microg x mol(-1) crea; P=0.024). This significant difference was only in female subjects (before: 59.8 microg x mol(-1) crea; after: 124.4 microg x mol(-1) crea; P=0.023). General linear models of repeated measurements showed that urinary excretions of Ni and Cr were associated with the number of restoration and the area of metal basis uncovered with porcelain.
CONCLUSIONDental restoration of Ni-Cr alloy might lead to the enhanced excretions of urinary Ni and Cr.
