Clinicopathological features and treatment of extremity bone metastasis in patients with endometrial carcinoma: a case report and review.
- Author:
Guo-qing JIANG
1
;
Yu-nong GAO
;
Min GAO
;
Hong ZHENG
;
Xin YAN
;
Wen WANG
;
Na AN
;
Kun CAO
Author Information
1. Department of Gynecologic Oncology, Peking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing, China.
- Publication Type:Case Reports
- MeSH:
Bone Neoplasms;
pathology;
secondary;
surgery;
Endometrial Neoplasms;
complications;
pathology;
surgery;
Female;
Humans;
Middle Aged
- From:
Chinese Medical Journal
2011;124(4):622-626
- CountryChina
- Language:English
-
Abstract:
Unlike other non-gynecologic solid tumors, such as breast cancer, lung cancer, metastasis to bone from endometrial carcinoma is rare, metastasis to extremity is extremely rare. We report a 51-year-old multiparous woman with FIGO Stage IVb Grade 2 endometrial adenocarcinoma which metastasized to left lower extremity bone. She received an amputation of left lower extremity below the knees, and a total abdominal hysterectomy and bilateral salpingo-oophorectomy, and followed by systemic chemotherapy, radiation therapy to the pelvis and progestational agent. She had a complete response to above treatments, and disease-free survival for 10 months. After recurrence, she received chemotherapy, radiotherapy and progestational agent once again. She had lived 56 months and is still alive by the time of report. Metastasis of endometrial carcinoma to extremity bone can rarely occur and should be considered when the patient with endometrial carcinoma complained of unexplained pain and swelling associated with extremity bone.
