Risk factors for intra-abdominal hypertension in children with sepsis.
- Author:
Du-Fei ZHANG
1
;
Xiao-Wei FENG
;
Tao LIN
;
Kai-Fang WU
Author Information
- Publication Type:Journal Article
- MeSH: Child; Child, Preschool; Critical Illness; Female; Humans; Infant; Intra-Abdominal Hypertension; etiology; therapy; Male; Multiple Organ Failure; complications; Risk Factors; Sepsis; complications; mortality
- From: Chinese Journal of Contemporary Pediatrics 2013;15(7):530-534
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study risk factors for the occurrence of intra-abdominal hypertension (IAH) in children with sepsis.
METHODSA nest case-control study was employed. According to intra-abdominal pressures (IAP) measured by cystometry, 119 children with sepsis were classified into normal IAP (control, n = 80) and IAH groups (n = 39). Risk factors for the occurrence of IAH were investigated by monovariable and multivariable logistic regression analysis.
RESULTSMonovariable analysis showed that there were significant differences in pediatric critical illness score (PCIS), procalcitonin (PCT) level, PaCO(2), blood lactate level, rates of intestinal or intra-abdominal infection, ascites, gastrointestinal dysfunction, mechanical ventilation, shock and multiple organ dysfunction syndrome (MODS) between the IAH and control groups (P < 0.05). Multivariable logistic regression analysis demonstrated that decreased PCIS, MODS, shock, gastrointestinal dysfunction and ascites were major risk factors for the occurrence of IAH.
CONCLUSIONSChildren with sepsis who have decreased PCIS, MODS, shock, gastrointestinal dysfunction and ascites are at risk for the occurrence of IAH.
