Isolation and identification of a new cucurbitacin from Picria fel-terrae.
- Author:
Jie-Ming ZOU
1
;
Li-Sheng WANG
;
Xue-Min MA
;
Ren-Bing SHI
;
Ya-Jian GUO
Author Information
- Publication Type:Journal Article
- MeSH: Molecular Structure; Plants, Medicinal; chemistry; Saponins; chemistry; isolation & purification; Scrophulariaceae; chemistry; Steroids; chemistry; isolation & purification
- From: Acta Pharmaceutica Sinica 2004;39(11):910-912
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo study compounds isolated from Picria fel-terrae.
METHODSThe chemical constituents were separated and purified by column chromatography on silica gel and MCI. Their structures were identified on the basis of spectral data (IR, UV, MS, ID NMR and 2D NMR).
RESULTSA new cucurbitacin, along with a known one, were obtained from the 60% EtOH extract of the whole plant.
CONCLUSIONThe new compound was identified as 11, 24-dioxo-5, 21-diene-cucurbit-3alpha-O-beta-D-xylopyranosyl-16alpha-O-alpha-L-rhamnopyranoside (dehydrobryogenin glycoside). The known one, hexanorcucurbitacin F, was obtained for the first time from Picria fel-terrae.
