Chemical constituents from the seeds of Annona squamosa.
- Author:
Jing-guang YU
1
;
Xiu-zhen LUO
;
Lan SUN
;
De-yu LI
;
Wen-hua HUANG
;
Chun-yu LIU
Author Information
- Publication Type:Journal Article
- MeSH: Annona; chemistry; Furans; chemistry; isolation & purification; Lactones; chemistry; isolation & purification; Molecular Conformation; Molecular Structure; Plants, Medicinal; chemistry; Seeds; chemistry
- From: Acta Pharmaceutica Sinica 2005;40(2):153-158
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo study the antitumor active constituents of the seeds from Annona squamosa L. (Annonaceae).
METHODSVarious chromatographic techniques were used to isolate and purify the constituents. Their physico-chemical properties and spectral data were determined to elucidate the structures.
RESULTSEleven compounds were isolated and identified as annonaceous acetogenins: squamocenin (1), annotemoyin-2 (2), reticulatain-2 (3), squamocin-I (4), squamocin-B (5), squamocin (6), motrilin (7), squamostatin-D (8), squamostatin-E (9), cherimolin-1 (10), cherimolin-2 (11) from the ethyl alcohol extract of A. squamosa L.
CONCLUSIONSquamocenin (1) is a new acetogenin. Annotemoyin-2 (2) and reticulatain-2 (3) were isolated from this plant for the first time.
