Vasectomy not associated with prostate cancer: a meta-analysis.
- Author:
Ling-feng TANG
1
;
Hui JIANG
;
Xue-jun SHANG
;
Lian-ming ZHAO
;
Quan BAI
;
Kai HONG
;
De-feng LIU
;
Jian-ming LIU
;
Ren-pei YUAN
;
Qian CHEN
;
Lu-lin MA
Author Information
- Publication Type:Journal Article
- MeSH: Humans; Male; Prostatic Neoplasms; epidemiology; etiology; Risk Factors; Vasectomy; adverse effects
- From: National Journal of Andrology 2009;15(6):545-550
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the association between vasectomy and prostate cancer.
METHODSWe searched comprehensively the databases, CBMDisc, CMCC, CMAC, CNKI (from 1978 to January 6, 2009), and PubMed (from 1965 to January 6, 2009) using the key words "vasectomy" and "prostate cancer", screened the retrieved literature according to the inclusion and exclusion criteria, performed a Meta-analysis with the software RevMan 4.2 after identification of the relevant data, and calculated the overall pooled OR (95% CI) as well as that of the association of prostate cancer with <20 and > or =20 yr vasectomy.
RESULTSA total of 20 088 cases and 232 506 controls in 27 reports (7 cohort and 20 case-control studies) were included in this investigation. The overall pooled OR (95% CI) was 1.10 (0.97-1.24), and those of <20 and > or =20 yr vasectomy were 0.94 (0.83-1.06) and 1.05 (0.90-1.23), respectively.
CONCLUSIONNo existing literature show any positive association between vasectomy and prostate cancer.
