Advances in the researches of spermatogenic protein, Ropporin.
- Author:
Jing CHEN
1
;
Zhi-ming CAI
;
Yao-ting GUI
Author Information
1. Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, China. gzchenjing@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
Animals;
Humans;
Male;
Membrane Proteins;
physiology;
Spermatogenesis;
rho GTP-Binding Proteins;
physiology
- From:
National Journal of Andrology
2009;15(9):833-835
- CountryChina
- Language:Chinese
-
Abstract:
Ropporin has been identified as a spermatogenic cell-specific protein and may be involved in sperm maturation, motility, capacitation, hyperactivation and acrosome reaction. However, latest studies have shown that Ropporin is expressed weakly in normal non-testis tissues and highly in hematologic malignancies. Its highly conservative expression in mammalians demonstrates its importance to life. This paper updates the characterization, expression and its distribution, and biological function of Ropporin, and the advances in the clinical researches of the protein.
