Occupational and residential exposure to electric and magnetic field and its relationship on acute myeloid leukemia in adults - A Meta-analysis
10.3760/cma.j.issn.0254-6450.2011.08.019
- VernacularTitle:职业暴露和生活接触的低频电磁场与成年人急性髓系白血病——基于病例对照研究的Meta分析
- Author:
Xing WANG
1
;
Xiao-Qin WANG
;
Jing-Wen GU
Author Information
1. 复旦大学附属华山医院
- Keywords:
Acute myeloid leukemia;
Risk factors;
Electromagnetic fields;
Case-control study;
Meta-analysis
- From:
Chinese Journal of Epidemiology
2011;32(8):821-826
- CountryChina
- Language:Chinese
-
Abstract:
Objective Studies had suggested that risk of leukemia might be associated with occupational or residential exposures to electromagnetic fields and varied at distance to and level of the exposure or type of occupations. Through pooled analyses, etiologic insight on the associations between exposure and disease might be explained. Methods We carried out a Meta-analysis based on primary data (1980-2010) from 9 studies related to the electric and magnetic fields exposure and acute myeloid leukemia in adults to assess whether the combined results, adjusted for potential confounding, would indicate an association between them. Results In this study the overall estimated OR value was 1.24(95%CI: 1.11-1.37). The odds ratios for exposure categories of 0.1-0.2 μT, ≥0.2 μT, compared with ＜0.1 μT, were 1.17(95%CI: 0.98-1.39) and 1.51 (95%CI: 1.15-1.98),respectively. Conclusion Through employing the alternate cut points, stratification by level of exposure or distance and the relation on different ways of exposure, there appeared consistent evidence of increased risk between acute myeloid leukemia in adults and the extremely low frequency-electromagnetic to field exposure.
